2022

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S. Del Sol-Fernández, P. Martínez-Vicente, P. Gomollón-Zueco, C. Castro-Hinojosa, L. Gutiérrez, R. M. Fratila, M. Moros - Magnetogenetics: Remote activation of cellular functions triggered by magnetic switches, Nanoscale, 2022, 14, 209

https://doi.org/10.1039/D1NR06303K

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J. Idiago-López, E. Moreno-Antolín, M. Eceiza, J. M. Aizpurua, V. Grazú, J. M. de la Fuente and R. M. Fratila* - From Bench to Cell: A Roadmap for Assessing the Bioorthogonal “Click” Reactivity of Magnetic Nanoparticles for Cell Surface Engineering, Bioconj. Chemistry, 2022, in press

https://pubs.acs.org/doi/10.1021/acs.bioconjchem.2c00230

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2021

 

Y. Fernández-Afonso, L. Asín, L. Beola, M. Moros, J. M. de la Fuente, R. M. Fratila, V. Grazu, L. Gutiérrez - Iron Speciation in Animal Tissues Using AC Magnetic Susceptibility Measurements: Quantification of Magnetic Nanoparticles, Ferritin, and Other Iron-Containing Species, ACS Appl. Bio Mater, 2021, in press

https://pubs.acs.org/doi/abs/10.1021/acsabm.1c01200

 

L. Beola, V. Grazú, Y. Fernández-Afonso, R. M. Fratila, M. de las Heras, J. M. de la Fuente, L. Gutiérrez, L. Asín - Critical Parameters to Improve Pancreatic Cancer Treatment Using Magnetic Hyperthermia: Field Conditions, Immune Response, and Particle Biodistribution, ACS Appl. Mater. Interfaces, 2021, 13, 12982

https://pubs.acs.org/doi/10.1021/acsami.1c02338

http://pubs.acs.org/articlesonrequest/AOR-67TDKKDGJGABCADUIEDA

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B. Pem, M. Ćurlin, D. Domazet Jurašin, V. Vrček, R. Barbir, V. Micek, R. M. Fratila, J. M. de la Fuente, I. Vinković Vrček - Fate and Transformation of Silver Nanoparticles in Different Biological Conditions, Beilstein J. Nanotechnol. 2021, 12, 665

https://doi.org/10.3762/bjnano.12.53

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J. Idiago-López, E. Moreno-Antolín, J. M. de la Fuente and R. M. Fratila* - Nanoparticles and bioorthogonal chemistry joining forces for improved biomedical applications, Nanoscale Adv., 2021, 3, 1261

https://pubs.rsc.org/en/content/articlelanding/2021/na/d0na00873g#!divAbstract

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S. Hildebrand, N. Löwa, H. Paysen, R. M. Fratila, L. Reverte Salisa, T. Trakoolwilaiwan, Z. Niu, G. Kasparis, S. F. Preuss, O. Kosch, J. M. de la Fuente, N. T. K. Thanh, F. Wiekhorst, and A. Pfeifer - Quantification of Lipoprotein Uptake in Vivo Using Magnetic Particle Imaging and Spectroscopy, ACS Nano, 2021, 15, 434

https://doi.org/10.1021/acsnano.0c03229

http://pubs.acs.org/articlesonrequest/AOR-GHCRGYCIFNXTP54NC9G4

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2020

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L. Beola, L. Asín, C. Roma-Rodrigues, Y. Fernández-Afonso, R. M. Fratila, D. Serantes, S. Ruta, R. Chantrell, A. R. Fernandes, P. V. Baptista, J. M. De La Fuente, V. Grazu, L. Gutiérrez - Intracellular number of magnetic nanoparticles modulates the apoptotic death pathway after magnetic hyperthermia treatment, ACS Appl. Mater. Interfaces, 2020,12, 43474

https://pubs.acs.org/doi/10.1021/acsami.0c12900

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S. Ruiz - Rincón, A. González - Orive, V. Grazú, R. M. Fratila*, J. M. de la Fuente, P. Cea - Altering model cell membranes by means of localized magnetic heating, Coll. Surf. B: Biointerfaces, 2020, 196, 111315

https://doi.org/10.1016/j.colsurfb.2020.111315

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2019

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M. Moros, J. Idiago-López, L. Asín, E. Moreno-Antolín, L. Beola, V. Grazú, R. M. Fratila*, L. Gutiérrez, J. M. de la Fuente - Triggering antitumoural drug release and gene expression by magnetic hyperthermia, Adv. Drug Deliv. Rev., 2019, 138, 326

https://www.sciencedirect.com/science/article/pii/S0169409X18302527?via%3Dihub

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2018

 

L. Beola, L. Asín, R. M. Fratila, V, Herrero, J. M. de la Fuente, V. Grazú, and L. Gutiérrez - Dual Role of Magnetic Nanoparticles as Intracellular Hotspots and Extracellular Matrix Disruptors Triggered by Magnetic Hyperthermia in 3D Cell Culture Models, ACS Appl. Mater. Interfaces, 2018, 10, 44301

https://pubs.acs.org/doi/10.1021/acsami.8b18270

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O. K. Arriortua, M. Insausti, L. Lezama, I. Gil de Muro, E. Garaio, J. M. de la Fuente, R. M. Fratila, M. P. Morales, R. Costa, M. Eceiza, M.Sagartzazu-Aizpurua, J. M. Aizpurua - RGD-Functionalized Fe3O4 nanoparticles for magnetic hyperthermia, Coll. Surf. B: Biointerfaces, 2018, 165, 315

https://www.sciencedirect.com/science/article/abs/pii/S0927776518301061?via%3Dihub

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P. Sanguiñedo, R. M. Fratila, M. B. Estevez, J. M. de la Fuente, V. Grazú, S. Alborés - Extracellular Biosynthesis of Silver Nanoparticles Using Fungi and Their Antibacterial Activity, Nano Biomed. Eng., 2018, 10, 165

http://nanobe.org/Data/View/502?type=100

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G. Stepien, M. Moros, M.Pérez-Hernández, M. Monge, L. Gutiérrez, R. M. Fratila, M. de las Heras, S. Menao Guillén, J. J. Puente Lanzarote, C. Solans, J. Pardo, J. M. de la Fuente - Effect of surface chemistry and associated protein corona on the long-term biodegradation of iron oxide nanoparticles in vivo, ACS Appl. Mater. Interfaces, 2018, 10, 4548

https://pubs.acs.org/doi/10.1021/acsami.7b18648

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2017

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R. M. Fratila*, M. Navascuez, J. Idiago-López, M. Eceiza, J. I. Miranda, J. M. Aizpurua, J. M. de la Fuente - Covalent immobilisation of magnetic nanoparticles on surfaces via strain-promoted azide–alkyne click chemistry, New J. Chem., 2017, 41, 10835

https://pubs.rsc.org/en/content/articlelanding/2017/NJ/C7NJ01822C#!divAbstract

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Y. Hernández, Y. Coello, R. M. Fratila, J. M. de la Fuente, T. A. Lionberger - Highly sensitive ratiometric quantification of cyanide in water with gold nanoparticles via Resonance Rayleigh Scattering, Talanta, 2017, 167, 51

https://www.sciencedirect.com/science/article/pii/S0039914017302102

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2016

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D. J. Grootendorst, R. M. Fratila, J. Pouw, B. Ten Haken, R. J. A. Van Wezel, S. Rottenberg, W. Steenbergen, S. Manohar, T. J. M. Ruers - Photoacoustic staging of nodal metastases using SPIOs: Comparison between in vivo, in toto and ex vivo imaging in a rat model, Biomedical Spectroscopy and Imaging, 2016, 5, 71

https://content.iospress.com/articles/biomedical-spectroscopy-and-imaging/bsi127

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R. M. Fratila, M. Moros, J. M. de la Fuente - Recent advances in biosensing using magnetic glyconanoparticles, Anal Bioanal Chem, 2016, 408,1783

https://link.springer.com/article/10.1007/s00216-015-8953-2

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2015

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M. V. Gomez, A. M. Rodriguez, A. de la Hoz, F. Jimenez-Marquez, R. M. Fratila, P. A. Barneveld, A. H. Velders - Determination of Kinetic Parameters within a Single Nonisothermal On-Flow Experiment by Nanoliter NMR Spectroscopy, Anal. Chem., 2015, 87, 10547

https://pubs.acs.org/doi/10.1021/acs.analchem.5b02811

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R. M. Fratila*, S. Rivera-Fernández, J. M. de la Fuente - Shape matters: synthesis and biomedical applications of high aspect ratio magnetic nanomaterials, Nanoscale, 2015, 7, 8233

 https://pubs.rsc.org/en/content/articlelanding/2015/nr/c5nr01100k#!divAbstract

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2014

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K. S. Wimbush, R. M. Fratila, D. Wang, D. Qi, C, Liang, L. Yuan, N. Yakovlev, K. P. Loh, D. N. Reinhoudt, A. H. Velders, C. A. Nijhuis - Bias induced transition from an ohmic to a nonohmic interface in supramolecular tunneling junctions with Ga2O3/EGaIn top electrodes, Nanoscale, 2014, 6, 11246

https://pubs.rsc.org/en/content/articlelanding/2014/nr/c4nr02933j#!divAbstract

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R. M. Fratila, M. V. Gomez, S. Sy´kora, A. H. Velders - Multinuclear nanoliter one-dimensional and two-dimensional NMR spectroscopy with a single non-resonant microcoil, Nat. Commun., 2014, 5:3025 doi: 10.1038/ncomms4025

https://www.nature.com/articles/ncomms4025

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J. M. Aizpurua,  R. M. Fratila*,  Z. Monasterio, N. Pérez-Esnaola, E. Andreieff, A. Irastorza, M. Sagartzazu-Aizpurua - Triazolium cations: from the ‘‘click’’ pool to multipurpose applications, New J. Chem., 2014, 38, 474

https://pubs.rsc.org/en/content/articlelanding/2014/nj/c3nj00667k#!divAbstract

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R. M. Fratila, S. G. Mitchell, P. del Pino, V. Grazu, J. M. de la Fuente - Strategies for the Biofunctionalization of Gold and Iron Oxide Nanoparticles, Langmuir, 2014, 30, 15057

https://pubs.acs.org/doi/10.1021/la5015658

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2013

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A. M. Leferink, R. M. Fratila, Maaike A. Koenrades, C. A. van Blitterswijk, A. Velders, L. Moroni - An Open Source Image Processing Method to Quantitatively Assess Tissue Growth after Non-Invasive Magnetic Resonance Imaging in Human Bone Marrow Stromal Cell Seeded 3D Polymeric Scaffolds, PLoS ONE, 2013, 9, e115000. doi:10.1371/journal.pone.0115000

https://journals.plos.org/plosone/article/figure?id=10.1371/journal.pone.0115000.g003

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I. Braceras, J. Oyarbide, P. Azpiroz, N. Briz, E. Ipiñazar, N. Álvarez, G. Atorrasagasti, R. M. Fratila, J. M. Aizpurua -  ‘‘Plasma-Click’’ Based Strategy for Obtaining Antibacterial Surfaces on Implants, Plasma Process. Polym., 2013, 10, 328

https://onlinelibrary.wiley.com/doi/abs/10.1002/ppap.201200058

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D. J. Grootendorst, R. M. Fratila, M. Visscher, B. Ten Haken, R. J. A. Van Wezel, S. Rottenberg, W. Steenbergen, S. Manohar, T. J. M. Ruers - Intra-operative ex vivo photoacoustic nodal staging in a rat model using a clinical superparamagnetic iron oxide nanoparticle dispersion, J. Biophotonics, 2013, 1–12, DOI 10.1002/jbio.201200204

https://onlinelibrary.wiley.com/doi/abs/10.1002/jbio.201200204

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I. Azcune, E. Balentová, M. Sagartzazu-Aizpurua, J. I. Santos, J. I. Miranda, R. M. Fratila*, J. M. Aizpurua - Modulating Lectin Inhibition with N-Glycosyl-1,2,3-triazole Scaffolds, Eur. J. Org. Chem., 2013, 2434

https://chemistry-europe.onlinelibrary.wiley.com/doi/abs/10.1002/ejoc.201201674

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D. J. Grootendorst, J. Jose,  R. M. Fratila, M. Visscher, A. H. Velders, B. Ten Haken, T. G. Van Leeuwen, W. Steenbergen, S. Manohar, T. J. M. Ruers - Evaluation of superparamagnetic iron oxide nanoparticles (Endorem®) as a photoacoustic contrast agent for intra-operative nodal staging, Contrast Media Mol. Imaging, 2013, 8, 83

https://onlinelibrary.wiley.com/doi/full/10.1002/cmmi.1498

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2012

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J. M. Aizpurua, M. Sagartzazu-Aizpurua, Z. Monasterio, I. Azcune, C. Mendicute, J. I. Miranda, E. García-Lecina, A. Altube, R. M. Fratila - Introducing Axial Chirality into Mesoionic 4,4'-Bis(1,2,3-triazole) Dicarbenes, Org. Lett., 2012, 14, 1866

https://pubs.acs.org/doi/abs/10.1021/ol3004657

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2011

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R. M. Fratila*, A. H. Velders - Small-Volume Nuclear Magnetic Resonance Spectroscopy, Annu. Rev. Anal. Chem., 2011, 4, 227

https://www.annualreviews.org/doi/abs/10.1146/annurev-anchem-061010-114024?journalCode=anchem

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R. de la Rica, R. M. Fratila, A. Szarpak, J. Huskens, A. H. Velders - Multivalent Nanoparticle Networks as Ultrasensitive Enzyme Sensors, Angew. Chem. Int. Ed., 2011, 50, 5704

https://onlinelibrary.wiley.com/doi/abs/10.1002/anie.201008189

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J. M. Aizpurua, M. Sagartzazu-Aizpurua, I. Azcune, J. I. Miranda, Z. Monasterio,  E. García-Lecina, R. M. Fratila - "Click" Synthesis of Nonsymmetrical 4,4′-Bis(1,2,3-triazolium) Salts, Synthesis, 2011, 2737

https://www.thieme-connect.com/products/ejournals/abstract/10.1055/s-0030-1260061

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J. M. Aizpurua, J. I. Ganboa, C. Palomo, I. Loinaz, J. Oyarbide, X. Fernandez, E. Balentová, R. M. Fratila, A. Jiménez, J. I. Miranda, A. Laso, S. Ávila, J. L. Castrillo - Cyclic RGD β-Lactam Peptidomimetics Induce Differential Gene Expression in Human Endothelial Cells, ChemBioChem, 2011, 12, 401

https://chemistry-europe.onlinelibrary.wiley.com/doi/abs/10.1002/cbic.201000572

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A. Adamczyk-Wozniak, R. M. Fratila, I. D. Madura, A. Pawełko, A. Sporzynski, M. Tumanowicz, A. H. Velders, J. Zyła - Reactivity of 2-formylphenylboronic acid toward secondary aromatic amines in amination–reduction reactions, Tetrahedron Letters, 2011, 52, 6639

https://www.sciencedirect.com/science/article/pii/S0040403911017163

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(31) I. Braceras, P. Azpiroz, N. Briz, R. M. Fratila, J. Oyarbide, E. Ipiñazar, N. Álvarez, G. Atorrasagasti, J. M. Aizpurua  - Plasma Polymerized Silylated Ciprofloxacin as an Antibiotic Coating, Plasma Process. Polym., 2011, 8, 599

https://onlinelibrary.wiley.com/doi/abs/10.1002/ppap.201000160

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2010

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J. M. Aizpurua, C. Palomo, R. M. Fratila, P. Ferrón, J. I. Miranda - Stereomodulating effect of remote groups on the NADH-mimetic reduction of alkyl aroylformates with 1,4-dihydronicotinamide-β-lactam amides, Tetrahedron, 2010, 66, 3187

https://www.sciencedirect.com/science/article/pii/S0040402010003273

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J. M. Aizpurua, I. Azcune, R. M. Fratila*, E. Balentová, M. Sagartzazu-Aizpurua, J. I. Miranda - “Click” Synthesis of Nonsymmetrical Bis(1,2,3-triazoles), Org. Lett., 2010, 12, 1584

https://pubs.acs.org/doi/10.1021/ol1003127

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2009

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J. M. Aizpurua, C. Palomo, R. M. Fratila, P. Ferrón, A. Benito, E. Gómez-Bengoa, J. I. Miranda, J. I. Santos -  Mechanistic Insights on the Magnesium(II) Ion-Activated Reduction of Methyl Benzoylformate with Chelated NADH Peptide β-Lactam Models, J. Org. Chem., 2009, 74, 6691

https://pubs.acs.org/doi/10.1021/jo901236d

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2007

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C. Palomo, J. M. Aizpurua, E. Balentová, A. Jiménez, J. Oyarbide, R. M. Fratila, J. I. Miranda - Synthesis of β-Lactam Scaffolds for Ditopic Peptidomimetics, Org. Lett., 2007, 9, 101

https://pubs.acs.org/doi/10.1021/ol0626241

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2006

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C. Palomo, J. M. Aizpurua, A. Benito, L. Cuerdo, R. M. Fratila, J. I. Miranda, A. Linden - Functionalization of N-[(Silyl)methyl]-β-lactam Carbanions with Carbon Electrophiles, J. Org. Chem., 2006, 71, 6368

https://pubs.acs.org/doi/10.1021/jo060537g

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2004

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C. Palomo, J. M. Aizpurua, I. Ganboa, A. Benito, L. Cuerdo, R. M. Fratila, A. Jiménez, I. Loinaz, J. I. Miranda, K. R. Pytlewska, A. Micle, A. Linden, Org. Lett., 2004, 6, 4443

https://pubs.acs.org/doi/10.1021/ol048348c

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2003

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C. Palomo, J. M. Aizpurua, A. Benito, J. I. Miranda, R. M. Fratila, C. Matute, M. Domercq, F. Gago, S. Martín-Santamaría, A. Linden - Development of a New Family of Conformationally Restricted Peptides as Potent Nucleators of β-Turns. Design, Synthesis, Structure, and Biological Evaluation of a β-Lactam Peptide Analogue of Melanostatin, J. Am. Chem. Soc., 2003, 125, 52, 16243

https://pubs.acs.org/doi/10.1021/ja038180a

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